Fulminant hepatic failure due to herpes simplex after hysteroscopy.

Journal Article (Journal Article)

BACKGROUND: Fulminant hepatic failure due to herpes simplex in healthy adults is a rare condition with a high mortality rate. The lack of specific symptoms and the absence of typical herpetic lesions in a majority of cases contribute to delayed diagnosis. CASE: We describe a fatal case of fulminant hepatic failure due to herpes simplex in a healthy woman presenting after laparoscopy and hysteroscopy for tubal infertility. The patient lacked evidence of mucocutaneous lesions or jaundice. The surgery likely contributed to viral dissemination. CONCLUSION: Although rare, disseminated herpes should be considered a possible cause of postsurgical pelvic infections, even in the absence of ulcerative lesions. Until a definitive diagnosis is made, antiviral therapy should be considered in patients with high fever, leukopenia, and abnormal liver function.

Full Text

Duke Authors

Cited Authors

  • Price, TM; Harris, JB

Published Date

  • November 2001

Published In

Volume / Issue

  • 98 / 5 Pt 2

Start / End Page

  • 954 - 956

PubMed ID

  • 11704219

International Standard Serial Number (ISSN)

  • 0029-7844

Digital Object Identifier (DOI)

  • 10.1016/s0029-7844(01)01511-3


  • eng

Conference Location

  • United States