Dorsal root entry zone lesions for the treatment of post-herpetic neuralgia.


Journal Article

Post-herpetic pain was treated in 12 patients using dorsal root entry zone ( DREZ ) lesions. All patients had failed to receive adequate pain relief from conservative therapy consisting of transcutaneous nerve stimulation, carbamazepine, and/or amitriptyline. Dorsal root entry zone lesions were made to include the involved dermatomes plus one-half of the dermatomes above and below the painful areas. Eight patients reported good pain relief with follow-up periods ranging from 6 to 21 months. A ninth patient obtained satisfactory pain relief, but the superior 1 cm of the original painful area was not included in the distribution of the DREZ lesions. Patients whose lesions were performed using a thermally controlled lesion probe suffered no significant postoperative neurological deficit. Dorsal root entry zone lesions appeared to be a satisfactory treatment for post-herpetic neuralgia in patients who have failed to respond to more conservative modes of therapy.

Full Text

Duke Authors

Cited Authors

  • Friedman, AH; Nashold, BS; Ovelmen-Levitt, J

Published Date

  • June 1, 1984

Published In

Volume / Issue

  • 60 / 6

Start / End Page

  • 1258 - 1262

PubMed ID

  • 6726370

Pubmed Central ID

  • 6726370

International Standard Serial Number (ISSN)

  • 0022-3085

Digital Object Identifier (DOI)

  • 10.3171/jns.1984.60.6.1258


  • eng

Conference Location

  • United States