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3-dimensional optimization of multiple arcs for stereotactic radiosurgery.

Publication ,  Journal Article
Weeks, KJ; Marks, L; Ray, SK; Spencer, DP; Turner, DA; Friedman, AH
Published in: Int J Radiat Oncol Biol Phys
April 30, 1993

PURPOSE: During linear accelerator-based radiosurgery, the physicians and physicists need to determine which combination of treatment arcs are "best" with regard to target coverage and incidental dose to adjacent structures. This is a complex problem, especially when targets are geometrically close to critical structures. The purpose of this article is to present a method to mathematically determine a set of arcs to produce desired target and normal structure dose distributions in linear accelerator radiosurgery. METHODS AND MATERIALS: Nonlinear least squares regression was used to determine the table angles and gantry angle arc ranges and their associated beam weights appropriate to linear accelerator radiosurgery. RESULTS: Three cases are presented: (a) critical structure close to target volume; (b) target volume too large for the largest collimator to cover the volume with one isocenter and a standard plan; (c) target volume located within one critical structure and close to another critical structure. The optimized treatment plans are all shown to be superior to a defined standard plan. CONCLUSION: The method successfully enables one to determine nonstandard arcs which achieve the desired results. In particular, the method enables one to find clinical treatment solutions, even when the desired results cannot be a priori defined.

Duke Scholars

Published In

Int J Radiat Oncol Biol Phys

DOI

ISSN

0360-3016

Publication Date

April 30, 1993

Volume

26

Issue

1

Start / End Page

147 / 154

Location

United States

Related Subject Headings

  • Technology, Radiologic
  • Radiosurgery
  • Radiation Dosage
  • Oncology & Carcinogenesis
  • Humans
  • 5105 Medical and biological physics
  • 3407 Theoretical and computational chemistry
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
 

Citation

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ICMJE
MLA
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Weeks, K. J., Marks, L., Ray, S. K., Spencer, D. P., Turner, D. A., & Friedman, A. H. (1993). 3-dimensional optimization of multiple arcs for stereotactic radiosurgery. Int J Radiat Oncol Biol Phys, 26(1), 147–154. https://doi.org/10.1016/0360-3016(93)90186-y
Weeks, K. J., L. Marks, S. K. Ray, D. P. Spencer, D. A. Turner, and A. H. Friedman. “3-dimensional optimization of multiple arcs for stereotactic radiosurgery.Int J Radiat Oncol Biol Phys 26, no. 1 (April 30, 1993): 147–54. https://doi.org/10.1016/0360-3016(93)90186-y.
Weeks KJ, Marks L, Ray SK, Spencer DP, Turner DA, Friedman AH. 3-dimensional optimization of multiple arcs for stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 1993 Apr 30;26(1):147–54.
Weeks, K. J., et al. “3-dimensional optimization of multiple arcs for stereotactic radiosurgery.Int J Radiat Oncol Biol Phys, vol. 26, no. 1, Apr. 1993, pp. 147–54. Pubmed, doi:10.1016/0360-3016(93)90186-y.
Weeks KJ, Marks L, Ray SK, Spencer DP, Turner DA, Friedman AH. 3-dimensional optimization of multiple arcs for stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 1993 Apr 30;26(1):147–154.
Journal cover image

Published In

Int J Radiat Oncol Biol Phys

DOI

ISSN

0360-3016

Publication Date

April 30, 1993

Volume

26

Issue

1

Start / End Page

147 / 154

Location

United States

Related Subject Headings

  • Technology, Radiologic
  • Radiosurgery
  • Radiation Dosage
  • Oncology & Carcinogenesis
  • Humans
  • 5105 Medical and biological physics
  • 3407 Theoretical and computational chemistry
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences