Immunological abnormalities in the tears of multiple sclerosis patients.
Journal Article (Journal Article)
IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system in MS patients, but did not differ from findings in patients with eye affections or wearing hard contact lenses.
Full Text
Duke Authors
Cited Authors
- Liedtke, W; Weller, M; Wiethölter, H; Dichgans, J
Published Date
- March 1992
Published In
Volume / Issue
- 85 / 3
Start / End Page
- 228 - 230
PubMed ID
- 1575010
International Standard Serial Number (ISSN)
- 0001-6314
Digital Object Identifier (DOI)
- 10.1111/j.1600-0404.1992.tb04034.x
Language
- eng
Conference Location
- Denmark