Immunological abnormalities in the tears of multiple sclerosis patients.

Journal Article (Journal Article)

IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system in MS patients, but did not differ from findings in patients with eye affections or wearing hard contact lenses.

Full Text

Duke Authors

Cited Authors

  • Liedtke, W; Weller, M; Wiethölter, H; Dichgans, J

Published Date

  • March 1992

Published In

Volume / Issue

  • 85 / 3

Start / End Page

  • 228 - 230

PubMed ID

  • 1575010

International Standard Serial Number (ISSN)

  • 0001-6314

Digital Object Identifier (DOI)

  • 10.1111/j.1600-0404.1992.tb04034.x


  • eng

Conference Location

  • Denmark