A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development.

Journal Article (Journal Article)

A physiologic model of the dynamics of fetoplacental unit dehydroepiandrosterone (HDEA) to estrogen conversion is presented. A mathematical representation of this model is included. The model is used in Part II to determine the rate constant of DHEA to estrogen conversion and to successfully identify those fetuses in jeopardy from placental insufficiency within the population studied. This presentation permits critical comprehension of the model without extensive mathematical background.

Full Text

Duke Authors

Cited Authors

  • Nagey, DA; Pupkin, MJ; MacKenna, J; Schomberg, DW; Crenshaw, C

Published Date

  • May 15, 1976

Published In

Volume / Issue

  • 125 / 2

Start / End Page

  • 249 - 255

PubMed ID

  • 131487

International Standard Serial Number (ISSN)

  • 0002-9378

Digital Object Identifier (DOI)

  • 10.1016/0002-9378(76)90602-5


  • eng

Conference Location

  • United States