Effect of magnesium on fetal heart rate variability using computer analysis.
Journal Article
We studied 16 women, at 32 weeks' or more gestation who required magnesium sulfate (MgSO4) therapy for preterm labor or preeclampsia. A 60-minute Doppler fetal heart rate (FHR) tracing, analyzed by the Oxford Sonicaid System 8000, was obtained for 1 hour before and 2 hours after each patient received intravenous MgSO4 therapy. Maternal serum Mg2+ levels were obtained at the second monitoring session. Matched paired measures of FHR parameters were compared with the Student's t test. After MgSO4 administration, we noted significant falls in long-term variability, short-term variability, and total acceleration (more than 10 beats/min) counts. Reduced short-term and overall variability occurred in all cases with maternal serum Mg2+ levels more than 4.6 mg/dL. Therapeutic maternal serum Mg2+ levels are linked with decreases in long-term and short-term FHR variability and acceleration counts. These findings should be considered when evaluating resting FHR baseline of patients thus treated.
Full Text
Duke Authors
Cited Authors
- Hiett, AK; Devoe, LD; Brown, HL; Watson, J
Published Date
- July 1995
Published In
Volume / Issue
- 12 / 4
Start / End Page
- 259 - 261
PubMed ID
- 7575830
Pubmed Central ID
- 7575830
International Standard Serial Number (ISSN)
- 0735-1631
Digital Object Identifier (DOI)
- 10.1055/s-2007-994468
Language
- eng
Conference Location
- United States