Chorioamnionitis: is continuation of antibiotic therapy necessary after cesarean section?

Journal Article (Clinical Trial;Journal Article)

OBJECTIVE: Our purpose was to determine whether the continuation of antibiotics postoperatively after cesarean section in patients whose labors were complicated by chorioamnionitis would reduce the incidence of endometritis. STUDY DESIGN: Patients with a clinical diagnosis of chorioamnionitis treated with ampicillin during labor and who required cesarean delivery for obstetric indications received preoperative intravenous clindamycin and gentamicin and were randomized into 2 groups. Group 1 received no scheduled postoperative antibiotics and group 2 continued to receive clindamycin 900 mg every 8 hours and gentamicin 1.5 mg/kg every 8 hours until afebrile for a minimum of 24 hours (temperature

Full Text

Duke Authors

Cited Authors

  • Turnquest, MA; How, HY; Cook, CR; O'Rourke, TP; Cureton, AC; Spinnato, JA; Brown, HL

Published Date

  • November 1998

Published In

Volume / Issue

  • 179 / 5

Start / End Page

  • 1261 - 1266

PubMed ID

  • 9822512

International Standard Serial Number (ISSN)

  • 0002-9378

Digital Object Identifier (DOI)

  • 10.1016/s0002-9378(98)70143-7


  • eng

Conference Location

  • United States