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Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome.

Publication ,  Journal Article
Perez, MC; Wilson, WA; Brown, HL; Scopelitis, E
Published in: J Perinatol
March 1991

Anticardiolipin antibodies (ACLA) have recently been associated with adverse fetal outcome. The prevalence of elevated ACLA has not been studied in unselected pregnant women, however. Twelve hundred unselected pregnant women were screened for IgG ACLA using an assay standardized by the first international workshop on ACLA. Fifteen (1.25%) were positive for IgG ACLA (greater than 3 SD above the mean) but only 0.5% had moderate to high levels of IgG ACLA (greater than 5 SD above the mean). Low levels of IgG ACLA were not associated with increased risk of fetal loss; however, 50% of women with moderate to high levels of antibody had fetal wastage. These findings further support the association of significantly elevated levels of IgG ACLA with fetal loss.

Duke Scholars

Published In

J Perinatol

ISSN

0743-8346

Publication Date

March 1991

Volume

11

Issue

1

Start / End Page

33 / 36

Location

United States

Related Subject Headings

  • Pregnancy Outcome
  • Pregnancy
  • Pediatrics
  • Male
  • Infant, Newborn
  • Immunoglobulin G
  • Humans
  • Fetal Death
  • Female
  • Cardiolipins
 

Citation

APA
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ICMJE
MLA
NLM
Perez, M. C., Wilson, W. A., Brown, H. L., & Scopelitis, E. (1991). Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome. J Perinatol, 11(1), 33–36.
Perez, M. C., W. A. Wilson, H. L. Brown, and E. Scopelitis. “Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome.J Perinatol 11, no. 1 (March 1991): 33–36.
Perez MC, Wilson WA, Brown HL, Scopelitis E. Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome. J Perinatol. 1991 Mar;11(1):33–6.
Perez, M. C., et al. “Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome.J Perinatol, vol. 11, no. 1, Mar. 1991, pp. 33–36.
Perez MC, Wilson WA, Brown HL, Scopelitis E. Anticardiolipin antibodies in unselected pregnant women. Relationship to fetal outcome. J Perinatol. 1991 Mar;11(1):33–36.

Published In

J Perinatol

ISSN

0743-8346

Publication Date

March 1991

Volume

11

Issue

1

Start / End Page

33 / 36

Location

United States

Related Subject Headings

  • Pregnancy Outcome
  • Pregnancy
  • Pediatrics
  • Male
  • Infant, Newborn
  • Immunoglobulin G
  • Humans
  • Fetal Death
  • Female
  • Cardiolipins