Outcome of infants delivered between 24 and 28 weeks' gestation in women with severe pre-eclampsia.

Journal Article (Journal Article)

OBJECTIVE: To determine whether there are differences in neonatal outcome between infants born to mothers with severe pre-eclampsia and those born to normotensive mothers with preterm labor and intact membranes between 24 and 28 weeks' gestation. MATERIALS AND METHODS: Over a 4-year period between 1991 and 1995, neonates of women with severe pre-eclampsia delivering between 24 and 28 weeks were matched for maternal age, antenatally assigned gestational age and mode of delivery to normotensive women delivering during the same period. RESULTS: Fifty-eight women with severe pre-eclampsia were matched to 58 normotensive controls who delivered as a result of preterm labor. Antenatal steroids were used more often in pre-eclamptic women (75% vs. 47%, p < 0.01). The mean birth weight of pre-eclamptic neonates was significantly lower than that of controls, 767 g vs. 989 g, respectively. Other neonatal complications were similar for both groups. Neonates of pre-eclamptics required longer ventilator support (21 vs. 16 median days, p = 0.03). Neonatal survival was similar for both groups (72% and 79% for pre-eclamptics and normotensives, respectively). CONCLUSIONS: Neonates born to patients with severe pre-eclampsia have similar survival but a lower birth weight and require longer ventilator support than neonates born to women with preterm labor.

Full Text

Duke Authors

Cited Authors

  • Hiett, AK; Brown, HL; Britton, KA

Published Date

  • October 1, 2001

Published In

Volume / Issue

  • 10 / 5

Start / End Page

  • 301 - 304

PubMed ID

  • 11730491

International Standard Serial Number (ISSN)

  • 1057-0802

Digital Object Identifier (DOI)

  • 10.1080/714904350


  • eng

Conference Location

  • United States