Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke.

Journal Article (Journal Article)

Previously reported methods of dynamic, contrast-enhanced, CT perfusion imaging in acute stroke have been promising but substantially limited by their dependence on very rapid rates of injection (typically 10-20 ml/s in an arm vein). Newly available deconvolution software permits the use of lower rates of injection (e. g., 3-4 ml/s), and rapidly provides maps of cerebral blood flow, cerebral blood volume and mean transit time. We report the potential of CT perfusion imaging performed with an injection rate of 4 ml/s to provide information on the extent of hemodynamic abnormality, and to help distinguish viable from nonviable ischemic tissue. The slower injection rates permitted by deconvolution analysis substantially enhance the practicality of CT perfusion imaging for studying stroke.

Full Text

Duke Authors

Cited Authors

  • Eastwood, JD; Provenzale, JM; Hurwitz, LM; Lee, TY

Published Date

  • March 2001

Published In

Volume / Issue

  • 43 / 3

Start / End Page

  • 223 - 226

PubMed ID

  • 11305754

International Standard Serial Number (ISSN)

  • 0028-3940

Digital Object Identifier (DOI)

  • 10.1007/s002340000528


  • eng

Conference Location

  • Germany