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Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke.

Publication ,  Journal Article
Eastwood, JD; Provenzale, JM; Hurwitz, LM; Lee, TY
Published in: Neuroradiology
March 2001

Previously reported methods of dynamic, contrast-enhanced, CT perfusion imaging in acute stroke have been promising but substantially limited by their dependence on very rapid rates of injection (typically 10-20 ml/s in an arm vein). Newly available deconvolution software permits the use of lower rates of injection (e. g., 3-4 ml/s), and rapidly provides maps of cerebral blood flow, cerebral blood volume and mean transit time. We report the potential of CT perfusion imaging performed with an injection rate of 4 ml/s to provide information on the extent of hemodynamic abnormality, and to help distinguish viable from nonviable ischemic tissue. The slower injection rates permitted by deconvolution analysis substantially enhance the practicality of CT perfusion imaging for studying stroke.

Duke Scholars

Published In

Neuroradiology

DOI

ISSN

0028-3940

Publication Date

March 2001

Volume

43

Issue

3

Start / End Page

223 / 226

Location

Germany

Related Subject Headings

  • Tomography, X-Ray Computed
  • Stroke
  • Regional Blood Flow
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Injections, Intravenous
  • Humans
  • Hemodynamics
  • Drug Administration Schedule
 

Citation

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ICMJE
MLA
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Eastwood, J. D., Provenzale, J. M., Hurwitz, L. M., & Lee, T. Y. (2001). Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke. Neuroradiology, 43(3), 223–226. https://doi.org/10.1007/s002340000528
Eastwood, J. D., J. M. Provenzale, L. M. Hurwitz, and T. Y. Lee. “Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke.Neuroradiology 43, no. 3 (March 2001): 223–26. https://doi.org/10.1007/s002340000528.
Eastwood JD, Provenzale JM, Hurwitz LM, Lee TY. Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke. Neuroradiology. 2001 Mar;43(3):223–6.
Eastwood, J. D., et al. “Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke.Neuroradiology, vol. 43, no. 3, Mar. 2001, pp. 223–26. Pubmed, doi:10.1007/s002340000528.
Eastwood JD, Provenzale JM, Hurwitz LM, Lee TY. Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke. Neuroradiology. 2001 Mar;43(3):223–226.
Journal cover image

Published In

Neuroradiology

DOI

ISSN

0028-3940

Publication Date

March 2001

Volume

43

Issue

3

Start / End Page

223 / 226

Location

Germany

Related Subject Headings

  • Tomography, X-Ray Computed
  • Stroke
  • Regional Blood Flow
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Injections, Intravenous
  • Humans
  • Hemodynamics
  • Drug Administration Schedule