Skip to main content

Evaluation of software for registration of contrast-enhanced brain MR images in patients with glioblastoma multiforme.

Publication ,  Journal Article
Barboriak, DP; Provenzale, JM
Published in: AJR Am J Roentgenol
July 2002

OBJECTIVE: We evaluated commercially available software that rapidly and automatically registers brain MR images on a clinical workstation, and we studied the accuracy of these registrations. SUBJECTS AND METHODS: Ten patients with a diagnosis of glioblastoma multiforme underwent contrast-enhanced inversion recovery prepared three-dimensional (3D) volumetric spoiled gradient-recalled acquisition in the steady state (SPGR) MR imaging (contiguous 1.5-mm slice thickness, 96-104 slices). After this imaging sequence, each patient was brought out of the head coil into a sitting position and then repositioned in the coil. The inversion recovery prepared 3D SPGR sequence was then repeated. A commercially available software program operating on a clinical workstation was used to automatically register the second inversion recovery prepared SPGR series to the first. The speed of registration was recorded. The accuracy of each registration was estimated by recording the coordinates of eight anatomic landmarks on the registered and reference series and by calculating the mean error among matching landmarks. RESULTS: In nine of 10 patients, the registration software produced a visually satisfactory registration. In one patient, a second registration was necessary to produce a satisfactory registration. The processing time for each iteration was 48.3 +/- 3.8 sec (mean +/- SD). The mean error in aligning matching anatomic landmarks ranged from 0.67 to 1.41 mm, with an overall mean of 1.18 mm. The largest error among matching landmarks was 2.3 mm. CONCLUSION: Commercially available registration software can automatically register 3D imaging volumes in less than 1 min. The mean error in registration was approximately equivalent to the dimensions of a single voxel.

Duke Scholars

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

July 2002

Volume

179

Issue

1

Start / End Page

245 / 250

Location

United States

Related Subject Headings

  • Software Validation
  • Reproducibility of Results
  • Registries
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Imaging, Three-Dimensional
  • Humans
  • Glioblastoma
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Barboriak, D. P., & Provenzale, J. M. (2002). Evaluation of software for registration of contrast-enhanced brain MR images in patients with glioblastoma multiforme. AJR Am J Roentgenol, 179(1), 245–250. https://doi.org/10.2214/ajr.179.1.1790245
Barboriak, Daniel P., and James M. Provenzale. “Evaluation of software for registration of contrast-enhanced brain MR images in patients with glioblastoma multiforme.AJR Am J Roentgenol 179, no. 1 (July 2002): 245–50. https://doi.org/10.2214/ajr.179.1.1790245.
Barboriak, Daniel P., and James M. Provenzale. “Evaluation of software for registration of contrast-enhanced brain MR images in patients with glioblastoma multiforme.AJR Am J Roentgenol, vol. 179, no. 1, July 2002, pp. 245–50. Pubmed, doi:10.2214/ajr.179.1.1790245.

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

July 2002

Volume

179

Issue

1

Start / End Page

245 / 250

Location

United States

Related Subject Headings

  • Software Validation
  • Reproducibility of Results
  • Registries
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Imaging, Three-Dimensional
  • Humans
  • Glioblastoma