The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.
Publication
, Journal Article
Provenzale, JM; Mukundan, S; Dewhirst, M
Published in: AJR Am J Roentgenol
September 2005
OBJECTIVE: Our purpose is to describe methods of assessing leakiness of the blood-brain barrier and explain mechanisms for exploiting the blood-brain barrier for therapeutic purposes. CONCLUSION: Knowledge of the workings of the blood-brain barrier is important for an understanding of the ways in which blood-brain barrier permeability may be used as a surrogate marker for drug therapeutic response. Manipulation of the blood-brain barrier may provide a means for selectively targeting tumors for drug delivery.
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Published In
AJR Am J Roentgenol
DOI
ISSN
0361-803X
Publication Date
September 2005
Volume
185
Issue
3
Start / End Page
763 / 767
Location
United States
Related Subject Headings
- Permeability
- Nuclear Medicine & Medical Imaging
- Neovascularization, Pathologic
- Magnetic Resonance Imaging
- Humans
- Contrast Media
- Brain Neoplasms
- Blood-Brain Barrier
- Biological Transport
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Provenzale, J. M., Mukundan, S., & Dewhirst, M. (2005). The role of blood-brain barrier permeability in brain tumor imaging and therapeutics. AJR Am J Roentgenol, 185(3), 763–767. https://doi.org/10.2214/ajr.185.3.01850763
Provenzale, James M., Srinivasan Mukundan, and Mark Dewhirst. “The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.” AJR Am J Roentgenol 185, no. 3 (September 2005): 763–67. https://doi.org/10.2214/ajr.185.3.01850763.
Provenzale JM, Mukundan S, Dewhirst M. The role of blood-brain barrier permeability in brain tumor imaging and therapeutics. AJR Am J Roentgenol. 2005 Sep;185(3):763–7.
Provenzale, James M., et al. “The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.” AJR Am J Roentgenol, vol. 185, no. 3, Sept. 2005, pp. 763–67. Pubmed, doi:10.2214/ajr.185.3.01850763.
Provenzale JM, Mukundan S, Dewhirst M. The role of blood-brain barrier permeability in brain tumor imaging and therapeutics. AJR Am J Roentgenol. 2005 Sep;185(3):763–767.
Published In
AJR Am J Roentgenol
DOI
ISSN
0361-803X
Publication Date
September 2005
Volume
185
Issue
3
Start / End Page
763 / 767
Location
United States
Related Subject Headings
- Permeability
- Nuclear Medicine & Medical Imaging
- Neovascularization, Pathologic
- Magnetic Resonance Imaging
- Humans
- Contrast Media
- Brain Neoplasms
- Blood-Brain Barrier
- Biological Transport
- Animals