In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus isolates from transplant and nontransplant patients.

Journal Article (Journal Article)

We performed in vitro antifungal checkerboard testing on 12 Aspergillus fumigatus clinical isolates (6 transplant recipients and 6 nontransplant patients) with three antifungal agents (amphotericin B, voriconazole, and caspofungin) and three immunosuppressants (FK506, cyclosporine, and rapamycin). We were not able to detect a difference in calcineurin inhibitor antifungal activity against isolates from transplant recipients and nontransplant patients.

Full Text

Duke Authors

Cited Authors

  • Steinbach, WJ; Singh, N; Miller, JL; Benjamin, DK; Schell, WA; Heitman, J; Perfect, JR

Published Date

  • December 2004

Published In

Volume / Issue

  • 48 / 12

Start / End Page

  • 4922 - 4925

PubMed ID

  • 15561883

Pubmed Central ID

  • PMC529228

International Standard Serial Number (ISSN)

  • 0066-4804

Digital Object Identifier (DOI)

  • 10.1128/AAC.48.12.4922-4925.2004


  • eng

Conference Location

  • United States