Can behavioural factors produce a sustained elevation of blood pressure? Some observations and a hypothesis.

Journal Article (Review)

A major problem confronting behavioural theories of hypertension, such as the reactivity hypothesis, is that stress is likely to be intermittent, whereas the early stages of hypertension appear to be characterized by an increase in the tonic level of blood pressure and sympathetic activity. Furthermore, intermittent sympathetic arousal (e.g. exercise, thigh-cuff compression) does not necessarily raise tonic blood pressure. A worksite-based study of occupational stress has indicated that people in high-stress jobs have increased blood pressure throughout the day and night, which is at least consistent with a behaviourally mediated resetting of the tonic blood pressure level. There is evidence that adrenaline is preferentially released in response to behavioural stresses. According to the 'adrenaline hypothesis', adrenaline can raise tonic blood pressure while noradrenaline does not. We therefore propose that the different long-term effects of behavioural stress and exercise on blood pressure can be explained by their differing effects on catecholamine release.

Full Text

Duke Authors

Cited Authors

  • Pickering, TG; Schnall, PL; Schwartz, JE; Pieper, CF

Published Date

  • December 1991

Published In

Volume / Issue

  • 9 / 8

Start / End Page

  • S66 - S68

PubMed ID

  • 1795207

International Standard Serial Number (ISSN)

  • 0952-1178

Language

  • eng

Conference Location

  • England