Three-dimensional structure of calmodulin.

Journal Article (Journal Article)

The three-dimensional structure of calmodulin has been determined crystallographically at 3.0 A resolution. The molecule consists of two globular lobes connected by a long exposed alpha-helix. Each lobe binds two calcium ions through helix-loop-helix domains similar to those of other calcium-binding proteins. The long helix between the lobes may be involved in interactions of calmodulin with drugs and various proteins.

Full Text

Duke Authors

Cited Authors

  • Babu, YS; Sack, JS; Greenhough, TJ; Bugg, CE; Means, AR; Cook, WJ

Published Date

  • May 2, 1985

Published In

Volume / Issue

  • 315 / 6014

Start / End Page

  • 37 - 40

PubMed ID

  • 3990807

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/315037a0


  • eng

Conference Location

  • England