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The role of tumor markers in gynecologic oncology.

Publication ,  Journal Article
Olt, G; Berchuck, A; Bast, RC
Published in: Obstet Gynecol Surv
September 1990

Human chorionic gonadotropin is a highly sensitive and specific tumor marker for gestational trophoblastic neoplasia that accurately reflects tumor volume and the clinical course of disease. In women with endodermal sinus tumors and embryonal carcinomas, alpha-fetoprotein usually is a reliable marker, and it accurately predicts the presence of yolk sac elements in mixed germ cell tumors. CA 125 is the most widely utilized tumor marker presently available for use in patients with epithelial ovarian cancer. It has utility in monitoring therapy and differentiating benign from malignant pelvic masses. Measurement of serial CA 125 levels in postmenopausal women may facilitate screening for occult early stage disease. In the future, monoclonal antibodies that recognize tumor-associated antigens may prove useful for radionuclide imaging.

Duke Scholars

Published In

Obstet Gynecol Surv

DOI

ISSN

0029-7828

Publication Date

September 1990

Volume

45

Issue

9

Start / End Page

570 / 577

Location

United States

Related Subject Headings

  • alpha-Fetoproteins
  • Obstetrics & Reproductive Medicine
  • Humans
  • Genital Neoplasms, Female
  • Female
  • Chorionic Gonadotropin
  • Carcinoembryonic Antigen
  • Biomarkers, Tumor
  • Antigens, Tumor-Associated, Carbohydrate
  • Antibodies, Monoclonal
 

Citation

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ICMJE
MLA
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Olt, G., Berchuck, A., & Bast, R. C. (1990). The role of tumor markers in gynecologic oncology. Obstet Gynecol Surv, 45(9), 570–577. https://doi.org/10.1097/00006254-199009000-00002
Olt, G., A. Berchuck, and R. C. Bast. “The role of tumor markers in gynecologic oncology.Obstet Gynecol Surv 45, no. 9 (September 1990): 570–77. https://doi.org/10.1097/00006254-199009000-00002.
Olt G, Berchuck A, Bast RC. The role of tumor markers in gynecologic oncology. Obstet Gynecol Surv. 1990 Sep;45(9):570–7.
Olt, G., et al. “The role of tumor markers in gynecologic oncology.Obstet Gynecol Surv, vol. 45, no. 9, Sept. 1990, pp. 570–77. Pubmed, doi:10.1097/00006254-199009000-00002.
Olt G, Berchuck A, Bast RC. The role of tumor markers in gynecologic oncology. Obstet Gynecol Surv. 1990 Sep;45(9):570–577.

Published In

Obstet Gynecol Surv

DOI

ISSN

0029-7828

Publication Date

September 1990

Volume

45

Issue

9

Start / End Page

570 / 577

Location

United States

Related Subject Headings

  • alpha-Fetoproteins
  • Obstetrics & Reproductive Medicine
  • Humans
  • Genital Neoplasms, Female
  • Female
  • Chorionic Gonadotropin
  • Carcinoembryonic Antigen
  • Biomarkers, Tumor
  • Antigens, Tumor-Associated, Carbohydrate
  • Antibodies, Monoclonal