A case of disseminated infection with Nocardia brasiliensis in a lung transplant recipient.

Journal Article (Journal Article)

BACKGROUND: Infection with Nocardia species is an increasingly recognized complication of solid organ transplantation. Nocardia asteroides accounts for most transplant-related nocardiosis, while Nocardia brasiliensis rarely causes infection in organ transplant recipients. METHODS: We describe a case of disseminated infection with N brasiliensis in a single-lung transplant recipient who also had concomitant infections with viral and fungal organisms. RESULTS: Although the mortality rate is high in immunocompromised patients with disseminated Nocardia infection, our patient responded favorably to prolonged antimicrobial therapy. CONCLUSIONS: This case illustrates that N brasiliensis, like N asteroides, produces pulmonary disease and dissemination in solid organ transplant recipients, and demonstrates the utility of prolonged treatment with trimethoprim-sulfamethoxazole in Nocardia infections.

Full Text

Duke Authors

Cited Authors

  • Palmer, SM; Kanj, SS; Davis, RD; Tapson, VF

Published Date

  • April 27, 1997

Published In

Volume / Issue

  • 63 / 8

Start / End Page

  • 1189 - 1190

PubMed ID

  • 9133485

International Standard Serial Number (ISSN)

  • 0041-1337

Digital Object Identifier (DOI)

  • 10.1097/00007890-199704270-00023


  • eng

Conference Location

  • United States