Mycobacterium abscessus chest wall and pulmonary infection in a cystic fibrosis lung transplant recipient.

Published

Journal Article

Mycobacterial infections are increasingly recognized in cystic fibrosis (CF) patients before transplant; however, knowledge about the clinical significance or spectrum of infections observed with mycobacterial infections in lung transplant recipients is still evolving. Herein, we report a case of infection with Mycobacterium abscessus in a CF lung transplant recipient. Despite aggressive treatment before and peri-operatively with anti-mycobacterial therapy, the patient developed skin and soft tissue infection of the incision and of bilateral breast implants, eventually leading to disseminated pulmonary infection and death. This report highlights the potential for M abscessus to cause post-transplant disease in CF patients undergoing lung transplant, despite peri-operative anti-mycobacterial therapy. Thus, pre-transplant colonization with M abscessus should be viewed as a strong relative, if not absolute, contraindication to lung transplantation. The combination of the virulent pre-transplant pathogen M abscessus and foreign bodies in the chest likely acted synergistically to contribute to the unfortunate outcome in this patient.

Full Text

Duke Authors

Cited Authors

  • Taylor, JL; Palmer, SM

Published Date

  • August 2006

Published In

Volume / Issue

  • 25 / 8

Start / End Page

  • 985 - 988

PubMed ID

  • 16890122

Pubmed Central ID

  • 16890122

Electronic International Standard Serial Number (EISSN)

  • 1557-3117

Digital Object Identifier (DOI)

  • 10.1016/j.healun.2006.04.003

Language

  • eng

Conference Location

  • United States