Laparoscopic removal of gonads containing on occult seminoma in a woman with complete androgen resistance.
A 20-year-old woman with complete androgen resistance (AR; 46,XY), underwent prophylactic laparoscopic gonadectomy because of the known increased risk of gonadal malignancy. The procedure was performed with electrocoagulation using a four-puncture technique. Pelvic and abdominal inspection revealed no gonadal or metastatic tumor. The testes and attached structures were retracted medially, and the peritoneum and gonadal vessels were incised after electrocoagulation, thereby removing the gonads from the sidewalls. The gonads were individually placed into a specimen retrieval bag and removed through the suprapubic cannula site. Pathologic examination revealed an occult 8-mm seminoma in the let gonad, as well as bilateral Sertoli cell hamartomas, fallopian tube remnants, and smooth muscle tissue (mullerian remnants) adjacent to the gonads. Postoperatively, tumor markers were normal, and abdominal and pelvic computerized tomographic scans and chest radiographs were negative for possible metastatic disease. This case confirms that laparoscopic removal of testes in women with AR is effective, safe, and quick. Because of normal-appearing gonad may contain an occult tumor, we recommend using a retrieval bag, which may prevent dissemination of potentially malignant cells that may occur with unprotected morcellation.
Duke Scholars
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Related Subject Headings
- Testis
- Testicular Neoplasms
- Seminoma
- Primary Prevention
- Obstetrics & Reproductive Medicine
- Male
- Laparoscopy
- Humans
- Female
- Disorders of Sex Development
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Testis
- Testicular Neoplasms
- Seminoma
- Primary Prevention
- Obstetrics & Reproductive Medicine
- Male
- Laparoscopy
- Humans
- Female
- Disorders of Sex Development