Laparoscopic removal of gonads containing on occult seminoma in a woman with complete androgen resistance.

Journal Article (Journal Article;Review)

A 20-year-old woman with complete androgen resistance (AR; 46,XY), underwent prophylactic laparoscopic gonadectomy because of the known increased risk of gonadal malignancy. The procedure was performed with electrocoagulation using a four-puncture technique. Pelvic and abdominal inspection revealed no gonadal or metastatic tumor. The testes and attached structures were retracted medially, and the peritoneum and gonadal vessels were incised after electrocoagulation, thereby removing the gonads from the sidewalls. The gonads were individually placed into a specimen retrieval bag and removed through the suprapubic cannula site. Pathologic examination revealed an occult 8-mm seminoma in the let gonad, as well as bilateral Sertoli cell hamartomas, fallopian tube remnants, and smooth muscle tissue (mullerian remnants) adjacent to the gonads. Postoperatively, tumor markers were normal, and abdominal and pelvic computerized tomographic scans and chest radiographs were negative for possible metastatic disease. This case confirms that laparoscopic removal of testes in women with AR is effective, safe, and quick. Because of normal-appearing gonad may contain an occult tumor, we recommend using a retrieval bag, which may prevent dissemination of potentially malignant cells that may occur with unprotected morcellation.

Full Text

Duke Authors

Cited Authors

  • Chantilis, SJ; McQuitty, DA; Preminger, GM; Marshburn, PB

Published Date

  • May 1994

Published In

Volume / Issue

  • 1 / 3

Start / End Page

  • 277 - 282

PubMed ID

  • 9050501

International Standard Serial Number (ISSN)

  • 1074-3804

Digital Object Identifier (DOI)

  • 10.1016/s1074-3804(05)81024-2


  • eng

Conference Location

  • United States