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Primary intraocular T-cell-rich large B-cell lymphoma.

Publication ,  Journal Article
Cummings, TJ; Stenzel, TT; Klintworth, G; Jaffe, GJ
Published in: Arch Pathol Lab Med
August 2005

We report a primary intraocular T-cell-rich large B-cell lymphoma in a 57-year-old woman who underwent 3 diagnostic vitrectomies for a presumed diagnosis of panuveitis. She developed no light perception in the left eye and underwent enucleation. Histopathologic and immunohistochemical studies on the enucleated globe disclosed a primary intraocular large B-cell lymphoma involving the choroid, vitreous, and retina. A large population of T cells was identified among the neoplastic B-cell population. B-cell immunoglobulin gene rearrangement and T-cell receptor gene rearrangement studies using the polymerase chain reaction method indicated that a monoclonal immunoglobulin kappa light chain population was present and that the T-cell population was not monoclonal. This case highlights the importance of interpreting cytologic features in vitreous aspirates in the context of the clinical situation.

Duke Scholars

Published In

Arch Pathol Lab Med

DOI

EISSN

1543-2165

Publication Date

August 2005

Volume

129

Issue

8

Start / End Page

1050 / 1053

Location

United States

Related Subject Headings

  • Treatment Outcome
  • T-Lymphocytes
  • Pathology
  • Middle Aged
  • Lymphoma, Large B-Cell, Diffuse
  • Lymphoma, B-Cell
  • Humans
  • Gene Rearrangement, T-Lymphocyte
  • Gene Rearrangement, B-Lymphocyte, Heavy Chain
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cummings, T. J., Stenzel, T. T., Klintworth, G., & Jaffe, G. J. (2005). Primary intraocular T-cell-rich large B-cell lymphoma. Arch Pathol Lab Med, 129(8), 1050–1053. https://doi.org/10.5858/2005-129-1050-PITLBL
Cummings, Thomas J., Timothy T. Stenzel, Gordon Klintworth, and Glenn J. Jaffe. “Primary intraocular T-cell-rich large B-cell lymphoma.Arch Pathol Lab Med 129, no. 8 (August 2005): 1050–53. https://doi.org/10.5858/2005-129-1050-PITLBL.
Cummings TJ, Stenzel TT, Klintworth G, Jaffe GJ. Primary intraocular T-cell-rich large B-cell lymphoma. Arch Pathol Lab Med. 2005 Aug;129(8):1050–3.
Cummings, Thomas J., et al. “Primary intraocular T-cell-rich large B-cell lymphoma.Arch Pathol Lab Med, vol. 129, no. 8, Aug. 2005, pp. 1050–53. Pubmed, doi:10.5858/2005-129-1050-PITLBL.
Cummings TJ, Stenzel TT, Klintworth G, Jaffe GJ. Primary intraocular T-cell-rich large B-cell lymphoma. Arch Pathol Lab Med. 2005 Aug;129(8):1050–1053.

Published In

Arch Pathol Lab Med

DOI

EISSN

1543-2165

Publication Date

August 2005

Volume

129

Issue

8

Start / End Page

1050 / 1053

Location

United States

Related Subject Headings

  • Treatment Outcome
  • T-Lymphocytes
  • Pathology
  • Middle Aged
  • Lymphoma, Large B-Cell, Diffuse
  • Lymphoma, B-Cell
  • Humans
  • Gene Rearrangement, T-Lymphocyte
  • Gene Rearrangement, B-Lymphocyte, Heavy Chain
  • Female