Virulence genes of poxviruses and reoviruses.

Journal Article (Review)

Identification of viral genes that specify virulence, however defined, is of critical importance for the design of viral vaccines. In particular, the targeted development not only of avirulent vaccine strains but also of viruses to be used as carriers for foreign genes depends on the inactivation or deletion of genes that harm the host. This paper illustrates approaches to identifying viral pathogenesis genes in two model systems involving cowpox virus and reovirus, respectively.

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Duke Authors

Patel, Dhavalkumar Dhirajlal
Pickup, David James

Cited Authors

Joklik, WK; Pickup, DJ; Patel, DD; Moody, MD

Published Date

April 1, 1988

Published In

Vaccine

Volume / Issue

6 / 2

Start / End Page

123 - 128

PubMed ID

2838983

International Standard Serial Number (ISSN)

0264-410X

Language

Conference Location

Netherlands