Virulence genes of poxviruses and reoviruses.
Journal Article (Review)
Identification of viral genes that specify virulence, however defined, is of critical importance for the design of viral vaccines. In particular, the targeted development not only of avirulent vaccine strains but also of viruses to be used as carriers for foreign genes depends on the inactivation or deletion of genes that harm the host. This paper illustrates approaches to identifying viral pathogenesis genes in two model systems involving cowpox virus and reovirus, respectively.
Full Text
Duke Authors
Cited Authors
- Joklik, WK; Pickup, DJ; Patel, DD; Moody, MD
Published Date
- April 1, 1988
Published In
Volume / Issue
- 6 / 2
Start / End Page
- 123 - 128
PubMed ID
- 2838983
Pubmed Central ID
- 2838983
International Standard Serial Number (ISSN)
- 0264-410X
Digital Object Identifier (DOI)
- 10.1016/s0264-410x(88)80013-6
Language
- eng
Conference Location
- Netherlands