Retroperitoneal fibrosis. A true connective tissue disease.

Journal Article (Journal Article;Review)

Retroperitoneal fibrosis, a disease that can occur at any age, is characterized by a periaortic fibrous mass that often surrounds the ureters, leading to ureteral obstruction. Patients who present with this disease may complain of flank pain and acute renal failure. There is a high correlation with atherosclerotic disease of the aorta, although the pathogenesis of this disease remains unknown. Although recommendations for therapy remain empiric, prednisone seems to be efficacious in treatment; tamoxifen also may be effective. Retroperitoneal fibrosis usually does not lead to long-term morbidity or affect survival.

Full Text

Duke Authors

Cited Authors

  • Gilkeson, GS; Allen, NB

Published Date

  • February 1996

Published In

Volume / Issue

  • 22 / 1

Start / End Page

  • 23 - 38

PubMed ID

  • 8907063

International Standard Serial Number (ISSN)

  • 0889-857X

Digital Object Identifier (DOI)

  • 10.1016/s0889-857x(05)70260-x


  • eng

Conference Location

  • United States