Retroperitoneal fibrosis. A true connective tissue disease.
Journal Article (Journal Article;Review)
Retroperitoneal fibrosis, a disease that can occur at any age, is characterized by a periaortic fibrous mass that often surrounds the ureters, leading to ureteral obstruction. Patients who present with this disease may complain of flank pain and acute renal failure. There is a high correlation with atherosclerotic disease of the aorta, although the pathogenesis of this disease remains unknown. Although recommendations for therapy remain empiric, prednisone seems to be efficacious in treatment; tamoxifen also may be effective. Retroperitoneal fibrosis usually does not lead to long-term morbidity or affect survival.
Full Text
Duke Authors
Cited Authors
- Gilkeson, GS; Allen, NB
Published Date
- February 1996
Published In
Volume / Issue
- 22 / 1
Start / End Page
- 23 - 38
PubMed ID
- 8907063
International Standard Serial Number (ISSN)
- 0889-857X
Digital Object Identifier (DOI)
- 10.1016/s0889-857x(05)70260-x
Language
- eng
Conference Location
- United States