Association of methotrexate, rheumatoid arthritis and lymphoma: report of 2 cases and literature review.

Journal Article (Journal Article;Review)

We describe 2 Caucasian men with rheumatoid arthritis (RA) who developed non-Hodgkin's lymphoma of identical histological type during treatment with low dose oral weekly methotrexate (MTX). Both patients had longstanding RA and had been treated with MTX for over 2 years at time of tumor diagnosis; neither had secondary Sjögren's syndrome. The oncogenic potential of MTX and RA arthritis is reviewed.

Full Text

Duke Authors

Cited Authors

  • Kingsmore, SF; Hall, BD; Allen, NB; Rice, JR; Caldwell, DS

Published Date

  • September 1992

Published In

Volume / Issue

  • 19 / 9

Start / End Page

  • 1462 - 1465

PubMed ID

  • 1433017

International Standard Serial Number (ISSN)

  • 0315-162X


  • eng

Conference Location

  • Canada