Hyperrenin-hyperaldosterone-dependent malignant hypertension in polyarteritis nodosa.
Publication
, Journal Article
Thel, MC; Mannon, RB; Allen, NB
Published in: South Med J
December 1993
We have described a patient, subsequently found to have polyarteritis, whose renin activity was 60 times normal, a level associated with malignant hypertension and severe renal artery stenosis. The severe hypertension and its resistance to multiple medications in the face of a dramatic response to low-dose enalapril imply the renin-angiotensin system was the primary pathophysiologic mechanism. We believe renin activity should be measured in hypertensive patients with polyarteritis. Furthermore, PAN should be in the differential diagnosis of hyperreninemic hypertension. ACE inhibitors should be strongly considered in the management of classical PAN-induced hypertension.
Duke Scholars
Published In
South Med J
DOI
ISSN
0038-4348
Publication Date
December 1993
Volume
86
Issue
12
Start / End Page
1400 / 1402
Location
United States
Related Subject Headings
- Renin
- Polyarteritis Nodosa
- Male
- Hypertension, Renal
- Hypertension, Malignant
- Humans
- General & Internal Medicine
- Aldosterone
- Adult
- 42 Health sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Thel, M. C., Mannon, R. B., & Allen, N. B. (1993). Hyperrenin-hyperaldosterone-dependent malignant hypertension in polyarteritis nodosa. South Med J, 86(12), 1400–1402. https://doi.org/10.1097/00007611-199312000-00017
Thel, M. C., R. B. Mannon, and N. B. Allen. “Hyperrenin-hyperaldosterone-dependent malignant hypertension in polyarteritis nodosa.” South Med J 86, no. 12 (December 1993): 1400–1402. https://doi.org/10.1097/00007611-199312000-00017.
Thel MC, Mannon RB, Allen NB. Hyperrenin-hyperaldosterone-dependent malignant hypertension in polyarteritis nodosa. South Med J. 1993 Dec;86(12):1400–2.
Thel, M. C., et al. “Hyperrenin-hyperaldosterone-dependent malignant hypertension in polyarteritis nodosa.” South Med J, vol. 86, no. 12, Dec. 1993, pp. 1400–02. Pubmed, doi:10.1097/00007611-199312000-00017.
Thel MC, Mannon RB, Allen NB. Hyperrenin-hyperaldosterone-dependent malignant hypertension in polyarteritis nodosa. South Med J. 1993 Dec;86(12):1400–1402.
Published In
South Med J
DOI
ISSN
0038-4348
Publication Date
December 1993
Volume
86
Issue
12
Start / End Page
1400 / 1402
Location
United States
Related Subject Headings
- Renin
- Polyarteritis Nodosa
- Male
- Hypertension, Renal
- Hypertension, Malignant
- Humans
- General & Internal Medicine
- Aldosterone
- Adult
- 42 Health sciences