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Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea.

Publication ,  Journal Article
Cegielski, JP; Msengi, AE; Dukes, CS; Mbise, R; Redding-Lallinger, R; Minjas, JN; Wilson, ML; Shao, J; Durack, DT
Published in: AIDS
February 1993

OBJECTIVE: To determine whether specific intestinal parasites are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN: A prospective, cross-sectional study. SETTING: Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania. SUBJECTS: All children aged 15 months to 5 years admitted with chronic diarrhea, and age-matched controls. METHODS: Standardized history, physical examination, HIV serology, and stool parasitology were evaluated for all subjects. We compared three groups: HIV-infected and non-HIV-infected children with chronic diarrhea and controls without diarrhea. MAIN OUTCOME MEASURES: Fecal parasites and nutritional status. RESULTS: Chronic diarrhea accounted for one-quarter of all cases of diarrheal disease in the defined age range, and children with chronic diarrhea were severely malnourished. Forty per cent of subjects with chronic diarrhea were HIV-seropositive. Although intestinal parasites were detected in approximately 50% of all three groups, diarrheagenic parasites were detected in up to 40% of children with chronic diarrhea. Blastocystis hominis was detected only in HIV-infected patients. CONCLUSIONS: HIV infection was common in children with chronic diarrhea, and parasitic agents of diarrhea may be important in children with chronic diarrhea both with and without HIV infection in this setting. B. hominis was more frequent in HIV-infected children. The immunocompromising effects of severe malnutrition may have diminished the difference between HIV-infected and non-HIV-infected children.

Duke Scholars

Published In

AIDS

DOI

ISSN

0269-9370

Publication Date

February 1993

Volume

7

Issue

2

Start / End Page

213 / 221

Location

England

Related Subject Headings

  • Virology
  • Tanzania
  • Prospective Studies
  • Male
  • Intestinal Diseases, Parasitic
  • Infant
  • Humans
  • HIV Infections
  • Female
  • Diarrhea
 

Citation

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MLA
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Cegielski, J. P., Msengi, A. E., Dukes, C. S., Mbise, R., Redding-Lallinger, R., Minjas, J. N., … Durack, D. T. (1993). Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea. AIDS, 7(2), 213–221. https://doi.org/10.1097/00002030-199302000-00009
Cegielski, J. P., A. E. Msengi, C. S. Dukes, R. Mbise, R. Redding-Lallinger, J. N. Minjas, M. L. Wilson, J. Shao, and D. T. Durack. “Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea.AIDS 7, no. 2 (February 1993): 213–21. https://doi.org/10.1097/00002030-199302000-00009.
Cegielski JP, Msengi AE, Dukes CS, Mbise R, Redding-Lallinger R, Minjas JN, et al. Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea. AIDS. 1993 Feb;7(2):213–21.
Cegielski, J. P., et al. “Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea.AIDS, vol. 7, no. 2, Feb. 1993, pp. 213–21. Pubmed, doi:10.1097/00002030-199302000-00009.
Cegielski JP, Msengi AE, Dukes CS, Mbise R, Redding-Lallinger R, Minjas JN, Wilson ML, Shao J, Durack DT. Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea. AIDS. 1993 Feb;7(2):213–221.

Published In

AIDS

DOI

ISSN

0269-9370

Publication Date

February 1993

Volume

7

Issue

2

Start / End Page

213 / 221

Location

England

Related Subject Headings

  • Virology
  • Tanzania
  • Prospective Studies
  • Male
  • Intestinal Diseases, Parasitic
  • Infant
  • Humans
  • HIV Infections
  • Female
  • Diarrhea