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Cytologic screening after hysterectomy for benign disease.

Publication ,  Journal Article
Piscitelli, JT; Bastian, LA; Wilkes, A; Simel, DL
Published in: Am J Obstet Gynecol
August 1995

OBJECTIVE: Our purpose was to determine the effectiveness of vaginal cytology tests after hysterectomy for benign disease. STUDY DESIGN: We studied a 10-year retrospective cohort of patients after hysterectomy (n = 697 women, 9074 woman years). Patients were excluded if they had any type of invasive gynecologic malignancy. The main outcome variable was development of a vaginal cytologic abnormality, evaluated with Kaplan-Meier estimates and proportional hazards regression. RESULTS: We found 33 abnormal cytology results; most were of little clinical significance except for two biopsy-proven dysplasia cases. When we controlled for age, the risk was 4.67 for patients with a history of a cervical cytologic abnormality (95% confidence interval 2.1 to 10.6). We needed 633 tests to detect one true positive case of vaginal dysplasia. CONCLUSIONS: The low incidence of vaginal dysplasia and carcinoma, combined with the high false-positive rate, supports decreasing the number of screening tests performed for these low-risk patients.

Duke Scholars

Published In

Am J Obstet Gynecol

DOI

ISSN

0002-9378

Publication Date

August 1995

Volume

173

Issue

2

Start / End Page

424 / 430

Location

United States

Related Subject Headings

  • Vaginal Smears
  • Vaginal Neoplasms
  • Vagina
  • Risk Factors
  • Retrospective Studies
  • Proportional Hazards Models
  • Obstetrics & Reproductive Medicine
  • Middle Aged
  • Life Tables
  • Hysterectomy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Piscitelli, J. T., Bastian, L. A., Wilkes, A., & Simel, D. L. (1995). Cytologic screening after hysterectomy for benign disease. Am J Obstet Gynecol, 173(2), 424–430. https://doi.org/10.1016/0002-9378(95)90262-7
Piscitelli, J. T., L. A. Bastian, A. Wilkes, and D. L. Simel. “Cytologic screening after hysterectomy for benign disease.Am J Obstet Gynecol 173, no. 2 (August 1995): 424–30. https://doi.org/10.1016/0002-9378(95)90262-7.
Piscitelli JT, Bastian LA, Wilkes A, Simel DL. Cytologic screening after hysterectomy for benign disease. Am J Obstet Gynecol. 1995 Aug;173(2):424–30.
Piscitelli, J. T., et al. “Cytologic screening after hysterectomy for benign disease.Am J Obstet Gynecol, vol. 173, no. 2, Aug. 1995, pp. 424–30. Pubmed, doi:10.1016/0002-9378(95)90262-7.
Piscitelli JT, Bastian LA, Wilkes A, Simel DL. Cytologic screening after hysterectomy for benign disease. Am J Obstet Gynecol. 1995 Aug;173(2):424–430.
Journal cover image

Published In

Am J Obstet Gynecol

DOI

ISSN

0002-9378

Publication Date

August 1995

Volume

173

Issue

2

Start / End Page

424 / 430

Location

United States

Related Subject Headings

  • Vaginal Smears
  • Vaginal Neoplasms
  • Vagina
  • Risk Factors
  • Retrospective Studies
  • Proportional Hazards Models
  • Obstetrics & Reproductive Medicine
  • Middle Aged
  • Life Tables
  • Hysterectomy