Seven-transmembrane receptors.

Journal Article (Journal Article;Review)

Seven-transmembrane receptors, which constitute the largest, most ubiquitous and most versatile family of membrane receptors, are also the most common target of therapeutic drugs. Recent findings indicate that the classical models of G-protein coupling and activation of second-messenger-generating enzymes do not fully explain their remarkably diverse biological actions.

Full Text

Duke Authors

Cited Authors

  • Pierce, KL; Premont, RT; Lefkowitz, RJ

Published Date

  • September 2002

Published In

Volume / Issue

  • 3 / 9

Start / End Page

  • 639 - 650

PubMed ID

  • 12209124

International Standard Serial Number (ISSN)

  • 1471-0072

Digital Object Identifier (DOI)

  • 10.1038/nrm908


  • eng

Conference Location

  • England