DNA immunization of infants: potential and limitations.

Journal Article (Journal Article;Review)

DNA immunization is a relatively new and efficacious approach to vaccination. Only recently have we begun to test the efficacy of DNA vaccines in infants. DNA vaccines for a retrovirus, hepatitis B, influenza, rabies, measles, tetanus toxoid, and sendai virus, have now been proven to induce cellular and humoral immune responses in infant animals. Here we review the field of DNA immunization of newborn animals, some new promising immunization strategies, and the rapid progress obtained in this field.

Full Text

Duke Authors

Cited Authors

  • Butts, C; Zubkoff, I; Robbins, DS; Cao, S; Sarzotti, M

Published Date

  • August 1998

Published In

Volume / Issue

  • 16 / 14-15

Start / End Page

  • 1444 - 1449

PubMed ID

  • 9711786

International Standard Serial Number (ISSN)

  • 0264-410X

Digital Object Identifier (DOI)

  • 10.1016/s0264-410x(98)00106-6

Language

  • eng

Conference Location

  • Netherlands