Cellular immune responses in neonates.
Publication
, Journal Article
Fadel, S; Sarzotti, M
Published in: Int Rev Immunol
2000
Reduced numbers of lymphocytes and antigen presenting cells have been described as some of the main factors responsible for antigenic tolerance or low responsiveness in neonates. However, by changing the parameters of immunization, such as dose of antigen and frequency of antigen presenting cells we and others have shown that neonates have the option of developing the same variety of immune responses seen in adults. Several aspects of the development of cellular immunity in human and murine neonates are reviewed in this article, with a special focus on the development of T cell mediated responses, from ontogeny to effector function.
Duke Scholars
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Published In
Int Rev Immunol
DOI
ISSN
0883-0185
Publication Date
2000
Volume
19
Issue
2-3
Start / End Page
173 / 193
Location
England
Related Subject Headings
- Vaccines
- T-Lymphocytes
- Mice
- Infant, Newborn
- Immunology
- Immunity, Cellular
- Humans
- Animals, Newborn
- Animals
- Adaptation, Physiological
Citation
APA
Chicago
ICMJE
MLA
NLM
Fadel, S., & Sarzotti, M. (2000). Cellular immune responses in neonates. Int Rev Immunol, 19(2–3), 173–193. https://doi.org/10.3109/08830180009088504
Fadel, S., and M. Sarzotti. “Cellular immune responses in neonates.” Int Rev Immunol 19, no. 2–3 (2000): 173–93. https://doi.org/10.3109/08830180009088504.
Fadel S, Sarzotti M. Cellular immune responses in neonates. Int Rev Immunol. 2000;19(2–3):173–93.
Fadel, S., and M. Sarzotti. “Cellular immune responses in neonates.” Int Rev Immunol, vol. 19, no. 2–3, 2000, pp. 173–93. Pubmed, doi:10.3109/08830180009088504.
Fadel S, Sarzotti M. Cellular immune responses in neonates. Int Rev Immunol. 2000;19(2–3):173–193.
Published In
Int Rev Immunol
DOI
ISSN
0883-0185
Publication Date
2000
Volume
19
Issue
2-3
Start / End Page
173 / 193
Location
England
Related Subject Headings
- Vaccines
- T-Lymphocytes
- Mice
- Infant, Newborn
- Immunology
- Immunity, Cellular
- Humans
- Animals, Newborn
- Animals
- Adaptation, Physiological