Type A behavior and elevated physiological and neuroendocrine responses to cognitive tasks.

Journal Article (Journal Article)

Qualitatively distinct patterns of cardiovascular and neuroendocrine responses were observed in male college students during mental work and during sensory intake task performance. During mental work, Type A (coronary-prone) subjects showed greater muscle vasodilatation and more enhanced secretion of norepinephrine, epinephrine, and cortisol than Type B subjects. During sensory intake, Type A hyperresponsivity was found for testosterone and, among those subjects with a positive family history of hypertension, for cortisol. As a demonstration of combined cardiovascular, sympathetic nervous system, and neuroendocrine hyperresponsivity to specific cognitive tasks in Type A subjects, this study breaks ground in the search for mechanisms mediating the increased coronary disease risk among Type A persons.

Full Text

Duke Authors

Cited Authors

  • Williams, RB; Lane, JD; Kuhn, CM; Melosh, W; White, AD; Schanberg, SM

Published Date

  • October 29, 1982

Published In

Volume / Issue

  • 218 / 4571

Start / End Page

  • 483 - 485

PubMed ID

  • 7123248

Pubmed Central ID

  • 7123248

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.7123248


  • eng

Conference Location

  • United States