Membrane viscoplastic flow.


Journal Article

In this paper, a theory of viscoplasticity formulated by Prager and Hohenemser is developed for a two-dimensional membrane surface and applied to the analysis of the flow of "microtethers" pulled from red blood cells attached to glass substrates. The viscoplastic flow involves two intrinsic material constants: yield shear and surface viscosity. The intrinsic viscosity for plastic flow of membrane is calculated to be 1 X 10(-2) dyn-s/cm from microtether flow experiments, three orders of magnitude greater than surface viscosities of lipid membrane components. The fluid dissipation is dominated by the flow of a structural matrix which has exceeded its yield shear. The yield shear is the maximum shear resultant that the membrane can sustain before it begins to deform irreversibly. The yield shear is found to be in the range 2-8 X 10(-2) dyn/cm, two or three orders of magnitude smaller than the isotropic tension required to lyse red cells.

Full Text

Duke Authors

Cited Authors

  • Evans, EA; Hochmuth, RM

Published Date

  • January 1, 1976

Published In

Volume / Issue

  • 16 / 1

Start / End Page

  • 13 - 26

PubMed ID

  • 1244887

Pubmed Central ID

  • 1244887

Electronic International Standard Serial Number (EISSN)

  • 1542-0086

International Standard Serial Number (ISSN)

  • 0006-3495

Digital Object Identifier (DOI)

  • 10.1016/s0006-3495(76)85659-7


  • eng