Comparison of the low-temperature crystallization of glasses in the ternary systems H2O-NaCl-dimethyl sulfoxide and H2O-NaCl-glycerol


Journal Article (Review)

Differential thermal analysis studies have resulted in quantitative evaluation of the transformation kinetics of unstable glassy phases formed during cooling of solutions from equivalent isoplethal sections in the H2O-NaCl-dimethyl-sulfoxide (DMSO) and H2O-NaCl-glycerol ternary systems. These ternary systems are of particular importance in the field of cryobiology, where knowledge of glassy phases may be especially crucial for long-term storage of biological materials at cryogenic temperatures. Activation energies for devitrification of glasses in both systems have been determined to be approximately 13 kcal/mole. The glasses were found to have approximately equal long-term stabilities. The DMSO-containing glasses appear to be more complex than glycerol-containing glasses because of the occurrence of a relatively high-temperature ternary eutectic reaction. The study of these systems appears to be a unique area for the cooperation of physical and biological scientists.

Full Text

Duke Authors

Cited Authors

  • Cocks, FH; Hildebrandt, WH; Shepard, ML

Published Date

  • December 1, 1975

Published In

Volume / Issue

  • 46 / 8

Start / End Page

  • 3444 - 3448

International Standard Serial Number (ISSN)

  • 0021-8979

Digital Object Identifier (DOI)

  • 10.1063/1.322066

Citation Source

  • Scopus