Skip to main content
Journal cover image

System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors.

Publication ,  Journal Article
Aljuri, AN; Bursac, N; Marini, R; Cohen, RJ
Published in: Acta astronautica
August 2001

Prolonged exposure to microgravity in space flight missions (days) impairs the mechanisms responsible for defense of arterial blood pressure (ABP) and cardiac output (CO) against orthostatic stress in the post-flight period. The mechanisms responsible for the observed orthostatic intolerance are not yet completely understood. Additionally, effective counter measures to attenuate this pathophysiological response are not available. The aim of this study was to investigate the ability of our proposed system identification method to predict closed-loop dynamic changes in TPR induced by changes in mean arterial pressure (MAP) and right atrial pressure (RAP). For this purpose we designed and employed a novel experimental animal model for the examination of arterial and cardiopulmonary baroreceptors in the dynamic closed-loop control of total peripheral resistance (TPR), and applied system identification to the analysis of beat-to-beat fluctuations in the measured signals. Grant numbers: NAG5-4989.

Duke Scholars

Published In

Acta astronautica

DOI

EISSN

1879-2030

ISSN

0094-5765

Publication Date

August 2001

Volume

49

Issue

3-10

Start / End Page

167 / 170

Related Subject Headings

  • Vascular Resistance
  • Sheep
  • Pressoreceptors
  • Models, Cardiovascular
  • Models, Animal
  • Least-Squares Analysis
  • Hypotension, Orthostatic
  • Cardiovascular Physiological Phenomena
  • Cardiac Output
  • Blood Pressure
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Aljuri, A. N., Bursac, N., Marini, R., & Cohen, R. J. (2001). System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors. Acta Astronautica, 49(3–10), 167–170. https://doi.org/10.1016/s0094-5765(01)00095-9
Aljuri, A. N., N. Bursac, R. Marini, and R. J. Cohen. “System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors.Acta Astronautica 49, no. 3–10 (August 2001): 167–70. https://doi.org/10.1016/s0094-5765(01)00095-9.
Aljuri AN, Bursac N, Marini R, Cohen RJ. System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors. Acta astronautica. 2001 Aug;49(3–10):167–70.
Aljuri, A. N., et al. “System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors.Acta Astronautica, vol. 49, no. 3–10, Aug. 2001, pp. 167–70. Epmc, doi:10.1016/s0094-5765(01)00095-9.
Aljuri AN, Bursac N, Marini R, Cohen RJ. System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors. Acta astronautica. 2001 Aug;49(3–10):167–170.
Journal cover image

Published In

Acta astronautica

DOI

EISSN

1879-2030

ISSN

0094-5765

Publication Date

August 2001

Volume

49

Issue

3-10

Start / End Page

167 / 170

Related Subject Headings

  • Vascular Resistance
  • Sheep
  • Pressoreceptors
  • Models, Cardiovascular
  • Models, Animal
  • Least-Squares Analysis
  • Hypotension, Orthostatic
  • Cardiovascular Physiological Phenomena
  • Cardiac Output
  • Blood Pressure