Three-dimensional cultures of cardiomyocytes for electrophysiological studies of cardiac muscle
It was hypothesized that 3D cultures of cardiac myocytes consisting of multiple layers of interconnected cells would better mimic the structure and function of native tissue. Dissociated neonatal rat ventricular myocytes were seeded on 3D biodegradable polymer scaffolds and cultivated in a rotating tissue culture bioreactor for 7 days. In general, significant data was obtained.
Bursac, N; Papadaki, M; White, J; Eisenberg, S; Freed, L
Annals of Biomedical Engineering
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