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High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography.

Publication ,  Journal Article
van Leeuwen, TG; Kulkarni, MD; Yazdanfar, S; Rollins, AM; Izatt, JA
Published in: Optics letters
November 1999

Color Doppler optical coherence tomography (CDOCT) is capable of precise velocity mapping in turbid media. Previous CDOCT systems based on the short-time Fourier transform have been limited to maximum flow velocities of the order of tens of millimeters per second. We describe a technique, based on interference signal demodulation at multiple frequencies, to extend the physiological relevance of CDOCT by increasing the dynamic range of measurable velocities to hundreds of millimeters per second. The physiologically important parameter of shear rate is also derived from CDOCT measurements. The measured flow-velocity profiles and shear-rate distributions correlate very well with theoretical predictions. The multiple demodulation technique, therefore, may be useful to monitor blood flow in vivo and to identify regions with high and low shear rates.

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Published In

Optics letters

DOI

EISSN

1539-4794

ISSN

0146-9592

Publication Date

November 1999

Volume

24

Issue

22

Start / End Page

1584 / 1586

Related Subject Headings

  • Optics
  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
  • 0906 Electrical and Electronic Engineering
  • 0206 Quantum Physics
  • 0205 Optical Physics
 

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van Leeuwen, T. G., Kulkarni, M. D., Yazdanfar, S., Rollins, A. M., & Izatt, J. A. (1999). High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography. Optics Letters, 24(22), 1584–1586. https://doi.org/10.1364/ol.24.001584
Leeuwen, T. G. van, M. D. Kulkarni, S. Yazdanfar, A. M. Rollins, and J. A. Izatt. “High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography.Optics Letters 24, no. 22 (November 1999): 1584–86. https://doi.org/10.1364/ol.24.001584.
van Leeuwen TG, Kulkarni MD, Yazdanfar S, Rollins AM, Izatt JA. High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography. Optics letters. 1999 Nov;24(22):1584–6.
van Leeuwen, T. G., et al. “High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography.Optics Letters, vol. 24, no. 22, Nov. 1999, pp. 1584–86. Epmc, doi:10.1364/ol.24.001584.
van Leeuwen TG, Kulkarni MD, Yazdanfar S, Rollins AM, Izatt JA. High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography. Optics letters. 1999 Nov;24(22):1584–1586.
Journal cover image

Published In

Optics letters

DOI

EISSN

1539-4794

ISSN

0146-9592

Publication Date

November 1999

Volume

24

Issue

22

Start / End Page

1584 / 1586

Related Subject Headings

  • Optics
  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
  • 0906 Electrical and Electronic Engineering
  • 0206 Quantum Physics
  • 0205 Optical Physics