High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography.


Journal Article

Color Doppler optical coherence tomography (CDOCT) is a noninvasive technique for simultaneous high spatial resolution (~20 aem) imaging and high velocity resolution (~500 aem/s) imaging flowmetry in living tissues. In this paper, we demonstrate a reconstruction method which overcomes fundamental limitations on Doppler flow mapping associated with both high- and low-speed imaging. This algorithm is successful in retaining the high velocity resolution of CDOCT while eliminating motion artifact caused by slow image acquisition in samples which exhibit repetitive motion. We demonstrate reconstruction of blood flow throughout a beating Xenopus laevis heart and surrounding vasculature using gated CDOCT reconstruction.

Full Text

Duke Authors

Cited Authors

  • Yazdanfar, S; Kulkarni, M; Izatt, J

Published Date

  • December 1997

Published In

Volume / Issue

  • 1 / 13

Start / End Page

  • 424 - 431

PubMed ID

  • 19377566

Pubmed Central ID

  • 19377566

Electronic International Standard Serial Number (EISSN)

  • 1094-4087

International Standard Serial Number (ISSN)

  • 1094-4087

Digital Object Identifier (DOI)

  • 10.1364/oe.1.000424


  • eng