Reproducing cardiac restitution properties using the Fenton-Karma membrane model.


Journal Article

Modern models of cardiac membranes are often highly complex and computationally expensive, particularly when used in long simulations of spatially extended models of cardiac tissue. Therefore, there is a need for simpler membrane models that preserve the features of the complex models deemed important. This communication describes an empirical procedure that was used to choose the parameters of the three-variable Fenton-Karma (FK3V) model to reproduce the restitution properties of the Courtemanche-Ramirez-Nattel model of atrial tissue. The resulting parameter values for the FK3V model and the sensitivity table for all its parameters are provided. Thus, this study gives insight into the behavior of the FK3V model and the effect of its parameters on restitution properties.

Full Text

Duke Authors

Cited Authors

  • Oliver, RA; Krassowska, W

Published Date

  • July 2005

Published In

Volume / Issue

  • 33 / 7

Start / End Page

  • 907 - 911

PubMed ID

  • 16060530

Pubmed Central ID

  • 16060530

Electronic International Standard Serial Number (EISSN)

  • 1573-9686

International Standard Serial Number (ISSN)

  • 0090-6964

Digital Object Identifier (DOI)

  • 10.1007/s10439-005-3948-3


  • eng