Acoustic radiation force impulse imaging of thermally- and chemically-induced lesions in soft tissues: preliminary ex vivo results.

Journal Article (Journal Article)

The ability of acoustic radiation force impulse (ARFI) imaging to visualize thermally- and chemically-induced lesions in soft tissues was investigated. Lesions were induced in freshly excised bovine liver samples. Chemical lesions were induced via the injection of formaldehyde and thermal lesions were created using a radiofrequency (RF) ablation system. Although conventional sonography was unable to visualize induced lesions, ARFI imaging was capable of monitoring lesion size and boundaries. Agreement was observed between lesion size in ARFI images and in results from pathology. The fact that ARFI imaging requires no additional equipment aside from that needed for conventional ultrasonic imaging makes it a promising modality for monitoring lesion development in situations where sonography is already involved as a guiding mechanism, such as in procedures requiring precise catheter placement.

Full Text

Duke Authors

Cited Authors

  • Fahey, BJ; Nightingale, KR; Stutz, DL; Trahey, GE

Published Date

  • March 2004

Published In

Volume / Issue

  • 30 / 3

Start / End Page

  • 321 - 328

PubMed ID

  • 15063514

Electronic International Standard Serial Number (EISSN)

  • 1879-291X

International Standard Serial Number (ISSN)

  • 0301-5629

Digital Object Identifier (DOI)

  • 10.1016/j.ultrasmedbio.2003.11.012


  • eng