The detection of breast microcalcifications with medical ultrasound.

Journal Article (Journal Article)

Microcalcifications are small crystals of calcium apatites which form in human tissue through a number of mechanisms. The size, morphology, and distribution of microcalcifications are important indicators in the mammographic screening for and diagnosis of various carcinomas in the breast. Although x-ray mammography is currently the only accepted method for detecting microcalcifications, its efficacy in this regard can be reduced in the presence of dense parenchyma. Current ultrasound scanners do not reliably detect microcalcifications in the size range of clinical interest. The results of theoretical, simulation, and experimental studies focused on the improvement of the ultrasonic visualization of microcalcifications are presented. Methods for estimating the changes in microcalcification detection performance which result from changes in aperture geometry or the presence of an aberrator are presented. An analysis of the relative efficacy of spatial compounding and synthetic receive aperture geometries in the detection of microcalcifications is described. The impact of log compression of the detected image on visualization is discussed. Registered high resolution ultrasound and digital spot mammography images of microcalcifications in excised breast carcinoma tissue and results from the imaging of suspected microcalcifications in vivo are presented.

Full Text

Duke Authors

Cited Authors

  • Anderson, ME; Soo, MS; Bentley, RC; Trahey, GE

Published Date

  • January 1997

Published In

Volume / Issue

  • 101 / 1

Start / End Page

  • 29 - 39

PubMed ID

  • 9000730

International Standard Serial Number (ISSN)

  • 0001-4966

Digital Object Identifier (DOI)

  • 10.1121/1.417973


  • eng

Conference Location

  • United States