Nanoprobes and nanobiosensors for monitoring and imaging individual living cells.

Journal Article (Review;Journal Article)

This article presents an overview of nanobiosensors and nanoprobes. The fabrication, operating principle, and applications of these systems and their capacity for in vivo analysis and optical imaging at the single-cell level are discussed. Recently the cross-disciplinary integration of nanotechnology, biology, and photonics has been revolutionizing important areas in molecular biology, especially diagnostics and therapy at the molecular and cellular levels. Nanobiosensors and nanoprobes are a relatively new class of biosensing and imaging devices that allow for analytical measurements in individual living cells. These devices have the capacity to sense individual chemical species in specific locations within a cell. This article discusses the usefulness and potential of these nanotechnology-based systems in biological research and their applications to monitoring individual living cells.

Full Text

Duke Authors

Cited Authors

  • Vo-Dinh, T; Kasili, P; Wabuyele, M

Published Date

  • March 2006

Published In

Volume / Issue

  • 2 / 1

Start / End Page

  • 22 - 30

PubMed ID

  • 17292112

Electronic International Standard Serial Number (EISSN)

  • 1549-9642

International Standard Serial Number (ISSN)

  • 1549-9634

Digital Object Identifier (DOI)

  • 10.1016/j.nano.2005.10.012


  • eng