Development of a DNA biochip for gene diagnosis
Publication
, Journal Article
Vo-Dinh, T; Wintenberg, AL; Ericson, MN; Isola, N; Alarie, JP
Published in: Proceedings of SPIE - The International Society for Optical Engineering
December 1, 1998
We describe a biochip based on an integrated circuit photodiode array for use in medical diagnostics. The biochip is a self-contained device which has photosensors, amplifiers, discriminators and logic circuitry on board. The development and evaluation of various microchip system components of the genosensor are discussed. The performance of the DNA biochip device is illustrated with fluorescence detection of DNA probes specific to gene fragments of the human immuno-deficiency virus 1 (HIV1) system. The usefulness and potential of the DNA biochip technology for rapid and cost-effective medical diagnostics is discussed.
Duke Scholars
Published In
Proceedings of SPIE - The International Society for Optical Engineering
DOI
ISSN
0277-786X
Publication Date
December 1, 1998
Volume
3253
Start / End Page
27 / 33
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4009 Electronics, sensors and digital hardware
- 4006 Communications engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Vo-Dinh, T., Wintenberg, A. L., Ericson, M. N., Isola, N., & Alarie, J. P. (1998). Development of a DNA biochip for gene diagnosis. Proceedings of SPIE - The International Society for Optical Engineering, 3253, 27–33. https://doi.org/10.1117/12.308046
Vo-Dinh, T., A. L. Wintenberg, M. N. Ericson, N. Isola, and J. P. Alarie. “Development of a DNA biochip for gene diagnosis.” Proceedings of SPIE - The International Society for Optical Engineering 3253 (December 1, 1998): 27–33. https://doi.org/10.1117/12.308046.
Vo-Dinh T, Wintenberg AL, Ericson MN, Isola N, Alarie JP. Development of a DNA biochip for gene diagnosis. Proceedings of SPIE - The International Society for Optical Engineering. 1998 Dec 1;3253:27–33.
Vo-Dinh, T., et al. “Development of a DNA biochip for gene diagnosis.” Proceedings of SPIE - The International Society for Optical Engineering, vol. 3253, Dec. 1998, pp. 27–33. Scopus, doi:10.1117/12.308046.
Vo-Dinh T, Wintenberg AL, Ericson MN, Isola N, Alarie JP. Development of a DNA biochip for gene diagnosis. Proceedings of SPIE - The International Society for Optical Engineering. 1998 Dec 1;3253:27–33.
Published In
Proceedings of SPIE - The International Society for Optical Engineering
DOI
ISSN
0277-786X
Publication Date
December 1, 1998
Volume
3253
Start / End Page
27 / 33
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4009 Electronics, sensors and digital hardware
- 4006 Communications engineering