A fiberoptic antibody-based biosensor with time-resolved detection


Journal Article

A phase-resolved fiberoptic antibody-based biosensor is desci ibed, which combines the biochemical specificity of antigen-antibody reaction, the high sensitivity of laser excitation, the versatility of fiberoptic sensors, and the selectivity of phase-resolved detection. The device can differentiate benzo(a)pyrene and benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene. The limit of detection of benzo(a)pyrene tetrol is in the attomole range (10-18moles). © 1990 SPIE.

Full Text

Duke Authors

Cited Authors

  • Vo-Dinh, T; Nolan, T; Cheng, YF; Alarie, JP; Sepaniak, MJ

Published Date

  • February 13, 1990

Published In

Volume / Issue

  • 1172 /

Start / End Page

  • 266 - 272

Electronic International Standard Serial Number (EISSN)

  • 1996-756X

International Standard Serial Number (ISSN)

  • 0277-786X

Digital Object Identifier (DOI)

  • 10.1117/12.963196

Citation Source

  • Scopus