Multi-functional biochip for medical diagnostics and pathogen detection

Journal Article

We describe a multi-functional biochip (MFB), which uses two different types of bioreceptors, including nucleic acid and antibody probes, on a single platform. The multi-functional capability of the MFB device for biomedical diagnostics is illustrated by measurements of DNA probes specific to gene fragments of Bacillus anthracis and antibody probes targeted to Escherichia coli. Calibration curves for monitoring pathogenic species using antibody probes against E. coli and DNA probes for B. anthracis illustrate the capability of the device for medical diagnostics and for quantitative detection of pathogenic agents. © 2003 Published by Elsevier Science B.V.

Full Text

Duke Authors

Cited Authors

  • Vo-Dinh, T; Griffin, G; Stokes, DL; Wintenberg, A

Published Date

  • April 20, 2003

Published In

Volume / Issue

  • 90 / 1-3

Start / End Page

  • 104 - 111

International Standard Serial Number (ISSN)

  • 0925-4005

Digital Object Identifier (DOI)

  • 10.1016/S0925-4005(03)00048-0

Citation Source

  • Scopus