Development of a multiarray biosensor for DNA diagnostics
Publication
, Journal Article
Vo-Dinh, T; Isola, N; Alarie, JP; Landis, D; Griffin, GD; Allison, S
Published in: Instrumentation Science and Technology
January 1, 1998
This work involves the development and evaluation of a multiarray biosensor for DNA diagnostics. The evaluation of various system components developed for the biosensor is discussed. The DNA probes labeled with visible and near infrared (NIR) dyes are evaluated. The detection system uses a two-dimensional charge-coupled device (CCD), Examples of application of gene probes in DNA hybridization experiments and in biomedical diagnosis (detection of the p53 cancer gene) are presented to illustrate the usefulness and potential of the biosensor device.
Duke Scholars
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Published In
Instrumentation Science and Technology
DOI
ISSN
1073-9149
Publication Date
January 1, 1998
Volume
26
Issue
5
Start / End Page
503 / 514
Related Subject Headings
- Analytical Chemistry
- 3401 Analytical chemistry
- 0301 Analytical Chemistry
Citation
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Chicago
ICMJE
MLA
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Vo-Dinh, T., Isola, N., Alarie, J. P., Landis, D., Griffin, G. D., & Allison, S. (1998). Development of a multiarray biosensor for DNA diagnostics. Instrumentation Science and Technology, 26(5), 503–514. https://doi.org/10.1080/10739149808000917
Vo-Dinh, T., N. Isola, J. P. Alarie, D. Landis, G. D. Griffin, and S. Allison. “Development of a multiarray biosensor for DNA diagnostics.” Instrumentation Science and Technology 26, no. 5 (January 1, 1998): 503–14. https://doi.org/10.1080/10739149808000917.
Vo-Dinh T, Isola N, Alarie JP, Landis D, Griffin GD, Allison S. Development of a multiarray biosensor for DNA diagnostics. Instrumentation Science and Technology. 1998 Jan 1;26(5):503–14.
Vo-Dinh, T., et al. “Development of a multiarray biosensor for DNA diagnostics.” Instrumentation Science and Technology, vol. 26, no. 5, Jan. 1998, pp. 503–14. Scopus, doi:10.1080/10739149808000917.
Vo-Dinh T, Isola N, Alarie JP, Landis D, Griffin GD, Allison S. Development of a multiarray biosensor for DNA diagnostics. Instrumentation Science and Technology. 1998 Jan 1;26(5):503–514.
Published In
Instrumentation Science and Technology
DOI
ISSN
1073-9149
Publication Date
January 1, 1998
Volume
26
Issue
5
Start / End Page
503 / 514
Related Subject Headings
- Analytical Chemistry
- 3401 Analytical chemistry
- 0301 Analytical Chemistry