Experimental and numerical analysis of short-pulse laser interaction with tissue phantoms containing inhomogeneities.

Journal Article (Journal Article)

The objective is to perform an experimental and numerical study to analyze short-pulse laser propagation through tissue phantoms without and with inhomogeneities embedded in them. For a short-pulse laser the observed optical signal has a distinct temporal shape, and the shape is a function of the medium properties. The scattered temporal transmitted and reflected optical signals are measured experimentally with a streak camera for tissue phantoms irradiated with a short-pulse laser source. A parametric study involving different scattering and absorption coefficients of tissue phantoms and inhomogeneities, as well as the detector positions and orientations, is performed. The temporal and spatial profiles of the scattered optical signals are compared with the numerical modeling results obtained by solving the transient radiative transport equation by using the discrete ordinates technique.

Full Text

Duke Authors

Cited Authors

  • Das, C; Trivedi, A; Mitra, K; Vo-Dinh, T

Published Date

  • September 2003

Published In

Volume / Issue

  • 42 / 25

Start / End Page

  • 5173 - 5180

PubMed ID

  • 12962398

Electronic International Standard Serial Number (EISSN)

  • 1539-4522

International Standard Serial Number (ISSN)

  • 1559-128X

Digital Object Identifier (DOI)

  • 10.1364/ao.42.005173


  • eng