Clinical experience with a multi-element ultrasonic hyperthermia system: analysis of treatment temperatures.

Journal Article (Journal Article)

A summary of tumour temperature data obtained from 31 patients who underwent 147 hyperthermia treatments with the Sonotherm 1000 ultrasonic system is presented. The treatment goal was to achieve a minimum of 42.0 degrees C in tumour for 60 min duration with normal tissues remaining below 43.0 degrees C. In 83% of treatments at least one measured tumour temperature reached or exceeded 42.0 degrees C at some time during the treatment. Nineteen per cent of these treatments had a time- and spatial-averaged temperature (measured in tumour) greater than or equal to 42.0 degrees C. A variety of anatomical sites were treated and these were grouped into four categories: groin/trunk, axilla, breast/chest wall and head/neck. Measured temperatures in tumours located in the groin and trunk sites were significantly higher (22% greater than or equal to 42 degrees C) than other locations. The head and neck treatment temperatures were significantly lower (8% of measured points greater than or equal to 42 degrees C.

Full Text

Duke Authors

Cited Authors

  • Samulski, TV; Grant, WJ; Oleson, JR; Leopold, KA; Dewhirst, MW; Vallario, P; Blivin, J

Published Date

  • 1990

Published In

Volume / Issue

  • 6 / 5

Start / End Page

  • 909 - 922

PubMed ID

  • 2250116

International Standard Serial Number (ISSN)

  • 0265-6736

Digital Object Identifier (DOI)

  • 10.3109/02656739009140972


  • eng

Conference Location

  • England