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Three-dimensional photon detection kernels and their application to SPECT reconstruction.

Publication ,  Journal Article
Smith, MF; Floyd, CE; Jaszczak, RJ; Coleman, RE
Published in: Phys Med Biol
March 1992

In single photon emission computed tomography (SPECT), three-dimensional photon detection kernels characterize the probabilities that photons emitted by radio-isotopes in different parts of the source region will be detected at particular projection pixels of the projection images. Monte Carlo modelling is used to study these kernels for the case of parallel hole collimators. The use of vectorized Monte Carlo computer code speeds the modelling computations. The contributions of direct and scattered photons to projection data in a transverse plane from neighbouring planes are significant for the case of uniform activity within a water-filled cylinder. A reconstruction method using the 3D kernels is proposed in which projection measurements in three adjacent planes are used simultaneously to estimate the source activity of the center plane. This multiple slice method accounts for the fact that photons detected in a given transverse plane may have originated in other transverse planes with different activity distributions. The matrix equations for image reconstruction are solved using generalized matrix inverses. The new method shows compensation for 3D photon detection effects when applied to projection data from a numerical simulation and a cardiac phantom experiment. Quantitation for the numerical study is improved compared with results from a single slice reconstruction method.

Duke Scholars

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

March 1992

Volume

37

Issue

3

Start / End Page

605 / 622

Location

England

Related Subject Headings

  • Tomography, Emission-Computed, Single-Photon
  • Radiation
  • Nuclear Medicine & Medical Imaging
  • Models, Structural
  • Image Processing, Computer-Assisted
  • Heart
  • 5105 Medical and biological physics
  • 1103 Clinical Sciences
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

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MLA
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Smith, M. F., Floyd, C. E., Jaszczak, R. J., & Coleman, R. E. (1992). Three-dimensional photon detection kernels and their application to SPECT reconstruction. Phys Med Biol, 37(3), 605–622. https://doi.org/10.1088/0031-9155/37/3/008
Smith, M. F., C. E. Floyd, R. J. Jaszczak, and R. E. Coleman. “Three-dimensional photon detection kernels and their application to SPECT reconstruction.Phys Med Biol 37, no. 3 (March 1992): 605–22. https://doi.org/10.1088/0031-9155/37/3/008.
Smith MF, Floyd CE, Jaszczak RJ, Coleman RE. Three-dimensional photon detection kernels and their application to SPECT reconstruction. Phys Med Biol. 1992 Mar;37(3):605–22.
Smith, M. F., et al. “Three-dimensional photon detection kernels and their application to SPECT reconstruction.Phys Med Biol, vol. 37, no. 3, Mar. 1992, pp. 605–22. Pubmed, doi:10.1088/0031-9155/37/3/008.
Smith MF, Floyd CE, Jaszczak RJ, Coleman RE. Three-dimensional photon detection kernels and their application to SPECT reconstruction. Phys Med Biol. 1992 Mar;37(3):605–622.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

March 1992

Volume

37

Issue

3

Start / End Page

605 / 622

Location

England

Related Subject Headings

  • Tomography, Emission-Computed, Single-Photon
  • Radiation
  • Nuclear Medicine & Medical Imaging
  • Models, Structural
  • Image Processing, Computer-Assisted
  • Heart
  • 5105 Medical and biological physics
  • 1103 Clinical Sciences
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences