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Inverse Monte Carlo as a unified reconstruction algorithm for ECT.

Publication ,  Journal Article
Floyd, CE; Jaszczak, RJ; Greer, KL; Coleman, RE
Published in: J Nucl Med
October 1986

Tomographic reconstruction for single photon emission computed tomography (SPECT) with simultaneous compensation for attenuation, scatter, and distance dependent collimator resolution is provided by an Inverse Monte Carlo (IMOC) reconstruction algorithm. A detection probability matrix is formed by Monte Carlo solution to the photon transport equation for SPECT acquisition from a unit source activity in each reconstruction source voxel. The measured projection vector will equal the product of this detection probability matrix with the unknown source distribution vector. The resulting large, nonsparse system of equations is solved for the source distribution using an iterative Maximum Likelihood EM estimator. Reconstruction of experimentally acquired projections from phantoms shows quantitative compensation for scatter and attenuation. Comparison with filtered backprojection (FBP) reconstruction shows an improvement in resolution recovery, contrast, and signal-to-noise for the IMOC algorithm. Reconstruction of clinical studies shows improved contrast, structural resolution, and noise characteristics.

Duke Scholars

Published In

J Nucl Med

ISSN

0161-5505

Publication Date

October 1986

Volume

27

Issue

10

Start / End Page

1577 / 1585

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Technology, Radiologic
  • Nuclear Medicine & Medical Imaging
  • Monte Carlo Method
  • Models, Structural
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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MLA
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Floyd, C. E., Jaszczak, R. J., Greer, K. L., & Coleman, R. E. (1986). Inverse Monte Carlo as a unified reconstruction algorithm for ECT. J Nucl Med, 27(10), 1577–1585.
Floyd, C. E., R. J. Jaszczak, K. L. Greer, and R. E. Coleman. “Inverse Monte Carlo as a unified reconstruction algorithm for ECT.J Nucl Med 27, no. 10 (October 1986): 1577–85.
Floyd CE, Jaszczak RJ, Greer KL, Coleman RE. Inverse Monte Carlo as a unified reconstruction algorithm for ECT. J Nucl Med. 1986 Oct;27(10):1577–85.
Floyd, C. E., et al. “Inverse Monte Carlo as a unified reconstruction algorithm for ECT.J Nucl Med, vol. 27, no. 10, Oct. 1986, pp. 1577–85.
Floyd CE, Jaszczak RJ, Greer KL, Coleman RE. Inverse Monte Carlo as a unified reconstruction algorithm for ECT. J Nucl Med. 1986 Oct;27(10):1577–1585.

Published In

J Nucl Med

ISSN

0161-5505

Publication Date

October 1986

Volume

27

Issue

10

Start / End Page

1577 / 1585

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Technology, Radiologic
  • Nuclear Medicine & Medical Imaging
  • Monte Carlo Method
  • Models, Structural
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences