Behavioral detection of tactile stimuli during 7-12 Hz cortical oscillations in awake rats.

Journal Article

Prominent 7-12 Hz oscillations in the primary somatosensory cortex (S1) of awake but immobile rats might represent a seizure-like state in which neuronal burst firing renders animals unresponsive to incoming tactile stimuli; others have proposed that these oscillations are analogous to human mu rhythm. To test whether rats can respond to tactile stimuli during 7-12 Hz oscillatory activity, we trained head-immobilized awake animals to indicate whether they could detect the occurrence of transient whisker deflections while we recorded local field potentials (LFPs) from microelectrode arrays implanted bilaterally in the S1 whisker representation area. They responded rapidly and reliably, suggesting that this brain rhythm represents normal physiological activity that does not preclude perception.

Full Text

Duke Authors

Cited Authors

  • Wiest, MC; Nicolelis, MAL

Published Date

  • September 2003

Published In

Volume / Issue

  • 6 / 9

Start / End Page

  • 913 - 914

PubMed ID

  • 12897789

International Standard Serial Number (ISSN)

  • 1097-6256

Digital Object Identifier (DOI)

  • 10.1038/nn1107

Language

  • eng

Conference Location

  • United States