The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.

Journal Article (Journal Article)

The Born charging equation predicts that the permeability of a phospholipid bilayer membrane to ions should depend markedly on the dielectric constant of the membrane. Increasing the dielectric constant of an artificial bilayer increases its permeability to perchlorate or thiocyanate by a factor of 1000, to a value comparable to that of mitochondrial membranes.

Full Text

Duke Authors

Cited Authors

  • Dilger, JP; McLaughlin, SG; McIntosh, TJ; Simon, SA

Published Date

  • December 7, 1979

Published In

Volume / Issue

  • 206 / 4423

Start / End Page

  • 1196 - 1198

PubMed ID

  • 228394

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.228394


  • eng

Conference Location

  • United States